Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Alfa Aesar™ 4-Methylumbelliferyl sulfate potassium salt, 98%

Click to view available options
Quantity:
500mg
1g
5g
15220-11-8
C10H7KO6S
294.318
MFCD00016970
CSOCSPXOODWGLJ-UHFFFAOYSA-M
4-methylumbelliferyl sulfate potassium salt, 2h-1-benzopyran-2-one, 4-methyl-7-sulfooxy-, potassium salt, 4-methylumbelliferyl sulfate, potassium salt, 2h-1-benzopyran-2-one, 4-methyl-7-sulfooxy-, potassium salt 1:1, potassium 4-methyl-2-oxo-2h-chromen-7-yl sulfate, potassium 4-methyl-2-oxochromen-7-yl sulfate, c10h7o6s.k, potassium 4-methyl-2-oxo-2h-1-benzopyran-7-yl sulphate, potassium 4-methylumbelliferyl sulfate
5044226
potassium;(4-methyl-2-oxochromen-7-yl) sulfate
CC1=CC(=O)OC2=C1C=CC(=C2)OS(=O)(=O)[O-].[K+]
15220-11-8
C10H7KO6S
294.318
MFCD00016970
CSOCSPXOODWGLJ-UHFFFAOYSA-M
4-methylumbelliferyl sulfate potassium salt, 2h-1-benzopyran-2-one, 4-methyl-7-sulfooxy-, potassium salt, 4-methylumbelliferyl sulfate, potassium salt, 2h-1-benzopyran-2-one, 4-methyl-7-sulfooxy-, potassium salt 1:1, potassium 4-methyl-2-oxo-2h-chromen-7-yl sulfate, potassium 4-methyl-2-oxochromen-7-yl sulfate, c10h7o6s.k, potassium 4-methyl-2-oxo-2h-1-benzopyran-7-yl sulphate, potassium 4-methylumbelliferyl sulfate
5044226
potassium;(4-methyl-2-oxochromen-7-yl) sulfate
CC1=CC(=O)OC2=C1C=CC(=C2)OS(=O)(=O)[O-].[K+]

Substrate for sulfatase

Applications
4-Methylumbelliferyl sulfate potassium salt is a fluorometric substrate for the determination of sulfatase. This substrate has been used in the discovery of tyrosine sulfotransferase inhibitors, particularly in P-selectin glycoprotein ligand-1 binding. This compound is virtually non-fluorescent until cleavage by sulfatase enzymes, then emits blue fluorescence (450 nm) with excitation at 360 nm. Use of this compound in high-throughput fluorescence based screening led to the discovery of several potent beta-arylsulfotransferase IV (beta-AST-IV) inhibitors.

Solubility
Soluble in water at 5mg/ml

Notes
Excitation wavelength, 334 nm; emission wavelength, 370nm (pH 10.4). Reaction product: excitiation wavelength, 360nm; emission wavelength, 449nm
Color White to Yellow
Quantity 500mg
Beilstein 3803203
Solubility Information Soluble in water at 5mg/ml
Formula Weight 294.32
Physical Form Powder
Percent Purity 98%
Chemical Name or Material 4-Methylumbelliferyl sulfate potassium salt

EINECSNumber : 239-272-2

TSCA : Yes

Recommended Storage : Store at -20°C