Tocris™ 4E1RCat

Protein translation inhibitor; blocks eIF4F subunit interaction

Manufacturer: Tocris™ 4215/50

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Catalog No. 42-155-0

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For Research Use Only


    Inhibitors 4E1RCat
    Purity >98
    Molecular Weight 478.45
    Quantity 50mg
    Product Type 4E1RCat

    Inhibitor of protein translation; blocks eIF4E:eIF4G and eIF4E:4E-BP1 interaction. Prevents assembly of the eIF4F complex and inhibits cap-dependent translation (IC50 ~4µM). Exhibits chemosensitizing properties.

    • Chemical Name: 4-[(3E)-3-[[5-(4-Nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl]benzoic acid
    • Formula: C28H18N2O6
    • CAS Number: 328998-25-0
    • Solubility: Soluble to 50mM in DMSO
    • Purity: >98

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