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Tocris™ 4E1RCat

Protein translation inhibitor; blocks eIF4F subunit interaction

Manufacturer:  Tocris™ 4215/10

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Catalog No. 42-151-0


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Disclaimers:

For Research Use Only


Specifications

Description

Inhibitor of protein translation; blocks eIF4E:eIF4G and eIF4E:4E-BP1 interaction. Prevents assembly of the eIF4F complex and inhibits cap-dependent translation (IC50 ~4µM). Exhibits chemosensitizing properties.
  • Chemical Name: 4-[(3E)-3-[[5-(4-Nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl]benzoic acid
  • Formula: C28H18N2O6
  • CAS Number: 328998-25-0
  • Solubility: Soluble to 50mM in DMSO
  • Purity: >98
Description & Specifications

Specifications

4E1RCat
>98
10mg
4E1RCat
478.45
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