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  6. 5-Bromo-2'-deoxyuridine, 99%, Thermo Scientific Chemicals

5-Bromo-2'-deoxyuridine, 99%, Thermo Scientific Chemicals

Catalog Number AAH2726003
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Quantity:
250 mg
1 g
5 g
59-14-3
C9H11BrN2O5
307.10
MFCD00006529
WOVKYSAHUYNSMH-RRKCRQDMSA-N
5-bromo-2'-deoxyuridine, broxuridine, bromodeoxyuridine, brdu, 5-bromodeoxyuridine, 5-brdu, budr, 5-bromouracil deoxyriboside, bromouracil deoxyriboside, 5-bromodesoxyuridine
6035
CHEBI:472552
5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O
59-14-3
C9H11BrN2O5
307.10
MFCD00006529
WOVKYSAHUYNSMH-RRKCRQDMSA-N
5-bromo-2'-deoxyuridine, broxuridine, bromodeoxyuridine, brdu, 5-bromodeoxyuridine, 5-brdu, budr, 5-bromouracil deoxyriboside, bromouracil deoxyriboside, 5-bromodesoxyuridine
6035
CHEBI:472552
5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O

Description

5-Bromo-2'-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-Bromo-2′-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.

Solubility
Soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY
Melting Point ∽190°C (decomposition)
Quantity 1 g
Beilstein 30395
Merck Index 14,1452
Solubility Information Soluble in water.
Optical Rotation +31° (c=1 in 0.1N HCl)
Formula Weight 307.1
Percent Purity 99%
Chemical Name or Material 5-Bromo-2'-deoxyuridine

Safety and Handling

Hazard Category H315-H319-H335-H341
Hazard Statement GHS H Statement
H341
Suspected of causing genetic defects.
Precautionary Statement P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362-P501c
EINECSNumber 200-415-9
RTECSNumber YU7350000
TSCA Yes
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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