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5-Carboxylcytosine (5-caC) Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Supplier: Active Motif 61226
Description
5-carboxylcytosine is the final oxidized derivative of 5-methylcytosine, a type of DNA methylation. 5-methylcytosine is oxidized to 5-hydroxymethylcytosine which is then oxidized to 5-formylcytosine and later to 5-carboxylcytosine. These oxidations are catalyzed by the Ten-Eleven Translocation (TET) enzyme family. 5-carboxylcytosine has been shown to cause reduced fidelity of RNA Polymerase II. Decreased levels of 5-hydroxymethylcytosine has been found in some cancers.Specifications
| 5-Carboxylcytosine (5-caC) | |
| Polyclonal | |
| Unconjugated | |
| Rabbit | |
| 10 μL | |
| Primary | |
| Antibody | |
| IgG |
| Dot Blot | |
| Conc. Not Determined | |
| whole serum with 30% glycerol and 0.035% sodium azide; pH | |
| This 5-Carboxylcytosine antibody was raised against 5-carboxylcytidine conjugated to kLH and recognizes 5-carboxylcytosine. | |
| RUO | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid | |
| Chemical |
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