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  7. 5'-Fluoroindirubinoxime, Tocris Bioscience™

5'-Fluoroindirubinoxime, Tocris Bioscience™

Catalog Number 403350
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
861214-33-7
C16H10FN3O2
295.27
MFCD18086923
LBUXOYSDWHGJNP-UHFFFAOYSA-N
5'-fluoroindirubinoxime, 5'-fluoro-1h,1'h-2,3' biindolylidene-3,2'dione 3-oxime, 5/'-fluoroindirubinoxime, d0t9fe, a05-a4b1-ii, 3z-5-fluoro-3-3e-3-hydroxyiminoindolin-2-ylidene indolin-2-one, 5-fluoro-3-3-hydroxyimino-1,3-dihydro-2h-indol-2-ylidene-1,3-dihydro-2h-indol-2-one
11580208
5'-fluoro-3-(hydroxyamino)-1H,2'H-[2,3'-biindol]-2'-one
ONC1=C(NC2=CC=CC=C12)C1=C2C=C(F)C=CC2=NC1=O
This item is not returnable. View return policy
861214-33-7
C16H10FN3O2
295.27
MFCD18086923
LBUXOYSDWHGJNP-UHFFFAOYSA-N
5'-fluoroindirubinoxime, 5'-fluoro-1h,1'h-2,3' biindolylidene-3,2'dione 3-oxime, 5/'-fluoroindirubinoxime, d0t9fe, a05-a4b1-ii, 3z-5-fluoro-3-3e-3-hydroxyiminoindolin-2-ylidene indolin-2-one, 5-fluoro-3-3-hydroxyimino-1,3-dihydro-2h-indol-2-ylidene-1,3-dihydro-2h-indol-2-one
11580208
5'-fluoro-3-(hydroxyamino)-1H,2'H-[2,3'-biindol]-2'-one
ONC1=C(NC2=CC=CC=C12)C1=C2C=C(F)C=CC2=NC1=O

Description

FLT3 inhibitor; displays antiproliferative activity

Inhibitor of FMS-like receptor tyrosine kinase-3 (FLT3) (IC50 = 15 nM). Displays selectivity for FLT3 against 6 other kinases including EGFR. Displays antiproliferative activity against the MV4;11 cell line (expressing constitutively active FLT3) and a number of cancer cell lines, including SNU-638 (stomach carcinoma) and HT-1080 (fibrosarcoma).
Quantity 50 mg
Formula Weight 295.27
Percent Purity >99%
Chemical Name or Material 5'-Fluoroindirubinoxime

Safety and Handling

Recommended Storage Store at +4°C
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