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5-Hydroxymethylcytosine (5-hmC) Mouse anti-Human, Mouse, Clone: 59.1, Active Motif™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

$135.30 - $534.00

Specifications

Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Antigen 5-Hydroxymethylcytosine (5-hmC)
Conjugate Unconjugated
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3030 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
40000
10 μg
Each for $135.30
Add to cart
 
50-199-3031 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
40900
50 μg
Each for $308.55
Add to cart
 
50-199-3029 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
39999
100 μg
Each for $534.00
Add to cart
 
Description

Description

5-hydroxymethylcytosine (5-hmC) has been recently discovered in mammalian DNA. 5-hmC results from the enzymatic conversion of 5-methylcytosine into 5-hydroxymethylcytosine by the TET family of oxygenases. Initially, the 5-hmC base had been identified in Purkinje neurons, in granule cells and embryonic stem cells where it is present at high levels (up to 0,6% of total nucleotides in Purkinje cells). A recent report indicates that 5-hmC is also abundant in brain tissue, especially in areas that are associated with higher cognitive functions.Early evidence suggests that 5-hmC may represent an intermediate in a new pathway which demethylates DNA, converting 5-mC to cytosine. Although its precise role has still to be shown, recent results indicate, however, that 5-hmC may play important roles distinct from 5-mC. This may open up entirely new perspectives in epigenetic studies.
Specifications

Specifications

Monoclonal
Primary
5-Hydroxymethylcytosine (5-hmC)
Unconjugated
SDS
Product Certifications
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