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5-Iodo-A-85380 dihydrochloride, Tocris Bioscience™
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Quantity:
10 mg
Description
A highly potent and subtype-selective agonist for the α4β2 and α6β2 nicotinic acetylcholine receptors. Activates α-CTx-MII-sensitive and -insensitive components of [3H]dopamine release from rat striatal synaptosomes, corresponding to α6β2 and α4β2 (EC50 values are 12.7 and ∽35 nM respectively). ∽5000-, 25000- and 140000-fold selective over α3β4, α7 and muscle nAChR receptors respectively.
Precursor also available.
Specifications
Quantity | 10 mg |
Formula Weight | 363.03 |
Percent Purity | >99% |
Chemical Name or Material | 5-Iodo-A-85380 dihydrochloride |
Safety and Handling
Recommended Storage | Desiccate at +4°C |
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