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5-Iodo-A-85380 dihydrochloride, Tocris Bioscience™

Catalog Number 151810
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Quantity:
10 mg
This item is not returnable. View return policy
1217837-17-6
C9H13Cl2IN2O
363.02
ZJVVFYWEBSHGBV-JZGIKJSDSA-N
s-3-azetidin-2-ylmethoxy-5-iodopyridine dihydrochloride, 5-iodo-a-85380 dihydrochloride, 3-2s-2-azetidinylmethoxy-5-iodopyridine dihydrochloride, 3-2s-azetidin-2-ylmethoxy-5-iodopyridine dihydrochloride
54758463
3-[[(2S)-azetidin-2-yl]methoxy]-5-iodopyridine;dihydrochloride
C1CNC1COC2=CC(=CN=C2)I.Cl.Cl
This item is not returnable. View return policy
1217837-17-6
C9H13Cl2IN2O
363.02
ZJVVFYWEBSHGBV-JZGIKJSDSA-N
s-3-azetidin-2-ylmethoxy-5-iodopyridine dihydrochloride, 5-iodo-a-85380 dihydrochloride, 3-2s-2-azetidinylmethoxy-5-iodopyridine dihydrochloride, 3-2s-azetidin-2-ylmethoxy-5-iodopyridine dihydrochloride
54758463
3-[[(2S)-azetidin-2-yl]methoxy]-5-iodopyridine;dihydrochloride
C1CNC1COC2=CC(=CN=C2)I.Cl.Cl

High affinity α4β2 and α6β2 subtype-selective agonist

A highly potent and subtype-selective agonist for the α4β2 and α6β2 nicotinic acetylcholine receptors. Activates α-CTx-MII-sensitive and -insensitive components of [3H]dopamine release from rat striatal synaptosomes, corresponding to α6β2 and α4β2 (EC50 values are 12.7 and ∽35 nM respectively). ∽5000-, 25000- and 140000-fold selective over α3β4, α7 and muscle nAChR receptors respectively.

Precursor also available.

Quantity 10 mg
Formula Weight 363.03
Percent Purity >99%
Chemical Name or Material 5-Iodo-A-85380 dihydrochloride
Recommended Storage Desiccate at +4°C
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