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5-Methylcytosine (5-mC) Rabbit anti-Human, Unconjugated, Polyclonal, Active Motif™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

$135.30 - $546.00

Specifications

Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen 5-Methylcytosine (5-mC)
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3274 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
61256
10 μL
Each for $135.30
Add to cart
 
50-199-3273 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
61255
100 μL
Each for $546.00
Add to cart
 
Description

Description

Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.
Specifications

Specifications

Polyclonal
Primary
5-Methylcytosine (5-mC)
Unconjugated
SDS
Product Certifications
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