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5-methylcytosine Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™
Mouse Recombinant Monoclonal Antibody
$100.30 - $454.30
Specifications
| Antigen | 5-methylcytosine |
|---|---|
| Concentration | 1 mg/mL |
| Applications | Dot Blot |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-3732
|
Active Motif
91188 |
10 μg |
Each for $100.30
|
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50-199-3731
|
Active Motif
91187 |
100 μg |
Each for $454.30
|
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Description
Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.Specifications
| 5-methylcytosine | |
| Dot Blot | |
| Unconjugated | |
| Mouse | |
| 140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5 | |
| This antibody was raised against 5-methylcytosine conjugated to kLH. | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| 5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3 | |
| IgG2a | |
| Protein A | |
| Antibody |
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