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5-(Trifluoromethoxy)isatin, 98%, Thermo Scientific Chemicals

Catalog Number AAB2549406
Click to view available options
Quantity:
1 g
5 g
169037-23-4
C9H4F3NO3
231.13
MFCD00192524
XHAJMVPMNOBILF-UHFFFAOYSA-N
5-trifluoromethoxy isatin, 5-trifluoromethoxy indoline-2,3-dione, 5-trifluoromethoxy-1h-indole-2,3-dione, 5-trifluoromethoxyisatin, 1h-indole-2,3-dione, 5-trifluoromethoxy, 5-trifluoromethoxy-2,3-indolinedione, buttpark 34\07-90, acmc-209dz9, d0zr2t
2732752
5-(trifluoromethoxy)-1H-indole-2,3-dione
C1=CC2=C(C=C1OC(F)(F)F)C(=O)C(=O)N2
169037-23-4
C9H4F3NO3
231.13
MFCD00192524
XHAJMVPMNOBILF-UHFFFAOYSA-N
5-trifluoromethoxy isatin, 5-trifluoromethoxy indoline-2,3-dione, 5-trifluoromethoxy-1h-indole-2,3-dione, 5-trifluoromethoxyisatin, 1h-indole-2,3-dione, 5-trifluoromethoxy, 5-trifluoromethoxy-2,3-indolinedione, buttpark 34\07-90, acmc-209dz9, d0zr2t
2732752
5-(trifluoromethoxy)-1H-indole-2,3-dione
C1=CC2=C(C=C1OC(F)(F)F)C(=O)C(=O)N2

5-(Trifluoromethoxy)isatin is used as a reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors and of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors. It is also used as a reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors and for preparation of indolone acetamides as antiseizure agents.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-(Trifluoromethoxy)isatin is used as a reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors and of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors. It is also used as a reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors and for preparation of indolone acetamides as antiseizure agents.

Solubility
Insoluble in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY
Melting Point 170°C to 172°C
Quantity 5 g
Solubility Information Insoluble in water.
Formula Weight 231.13
Percent Purity 98%
Chemical Name or Material 5-(Trifluoromethoxy)isatin
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only

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