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ACROBiosystems Recombinant Protein;Human CD155 / PVR Protein, Fc Tag;HEK293;100UG;CD5,CD155,PVR,FLJ25946,PVS,TAGE4,HVED,NECL5,NECL-5,TAGE-4

Manufacturer:  ACROBiosystems CD5H5251100UG


Recombinant Protein;Human CD155 / PVR Protein, Fc Tag;100UG;Human CD155, Fc Tag (CD5-H5251) is expressed from human 293 cells (HEK293). It contains AA Trp 21 - Asn 343 (Accession # AAH15542).;This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 61.7 kDa. The protein migrates as 95-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.;Immobilized Human CD155, Fc Tag (Cat. No. CD5-H5251) at 5 μg/mL (100 μL/well) can bind Biotinylated Human TIGIT, His Tag (Cat. No. TIT-H82E5) with a linear range of 5-78 ng/mL (QC tested).;FACS assay shows that recombinant Human CD155, Fc Tag (Cat .No. CD5-H5251) can bind to 293T cell overexpressing human TIGIT. The concentration of CD155 is 1 μg/ml (Routinely tested).;FACS analysis shows that the binding of Human CD155, Fc Tag to 293T overexpressing TIGIT was inhibited by increasing concentration of neutralizing Anti-Human TIGIT MAb. The concentration of CD155 used is 1 μg/ml. The IC50 is 0.09422

Catalog No. 50-108-9527

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