ACROBiosystems Recombinant Protein;Human Clusterin / CLUS Protein;HEK293;100UG;CLU,CLU,Clusterin,AAG4,APOJ,CLI,KUB1,SGP-2,SGP2,SP-40,TRPM-2,TRPM2
Manufacturer: ACROBiosystems CLUH5227100UG
Recombinant Protein;Human Clusterin / CLUS Protein;100UG;Recombinant Human CLUS /Clusterin Protein (rh CLUS / Clusterin) Asp23-Arg227 (β chain) & Ser228-Glu449 (α chain) (Accession # NP_001822.3) was produced in human 293 cells (HEK293) at ACROBiosystems.;rh CLUS / Clusterin is fused with 6 ×His tag at the C terminus, and has a calculated MW of 50.9 kDa (Asp23-Glu449, α chain 24.5kDa + β chain 27kDa). The recombinant rh CLUS / Clusterin (Asp23-Glu 449) was cleaved into α chain and β chain, which form a heterodimer linked by disulfide bonds. DTT reduced protein migrates as 39 kDa and 40 kDa bands in SDS-PAGE due to glycosylation, corresponding to the cleaved β chain, and α chain respectively.
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