ACROBiosystems ACROBiosystems Anti-Bevacizumab Antibodies (recommended for PK/PD)
Manufacturer: ACROBiosystems BEBY10100UG
Antibody;100UG;IgG1/kappa;Recognizes Bevacizumab specifically, no cross reactivity with other humanized antibodies.;Mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Bevacizumab F(ab')2.; ;Detection of bevacizumab by bridging ELISA in serum. Immobilized Anti-Bevacizumab Antibodies (recommended for PK/PD) (Cat. No. BEB-Y10) at 2 μg/mL, add increasing concentrations of bevacizumab (10% human serum) and then add Biotinylated Anti-Bevacizumab Antibodies (recommended for PK/PD) (Cat. No. BEB-BY13) at 2 μg/mL. Detection was performed using HRP-conjugated streptavidin with a sensitivity of 0.4 μg/mL. ;Immobilized bevacizumab at 1 μg/mL (100 μL/well) can bind Anti-Bevacizumab Antibodies (recommended for PK/PD) (Cat. No. BEB-Y10) with a linear range of 25-0.39 μg/mL.
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