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53BP1 Mouse anti-Human, Clone: OTI2H6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526830

Catalog No. PIMA526830


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Description

Description

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.
Specifications

Specifications

53BP1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q12888
53BP1, p202, p53-binding protein 1, p53BP1, tumor protein 53-binding protein, 1, tumor protein p53-binding protein, 1, tumor suppressor p53-binding protein 1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
7158
Immunohistochemistry (Paraffin), Western Blot
OTI2H6
Unconjugated
TP53BP1
Liquid
TP53BP1
Human recombit protein fragment corresponding to amino acids 1-300 of TP53BP1 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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