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90K/Mac-2BP Mouse anti-Human, Clone: SP-2, eBioscience™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen BMS146

Catalog No. 50-178-05


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Description

Description

Description: BMS146 specifically recognizes Mac-2 (galectin-3) mucin-like binding domain of human 90K/Mac-2BP. Mac-2BP is a highly glycosylated protein that plays a major role in cancer research. Elevated levels in sera have been found in many patients suffering from various types of cancer or viral infections. Applications Tested: Immunohistochemistry (Paraffin), Western Blotting. Purity: >95%.

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
Specifications

Specifications

90K/Mac-2BP
Monoclonal
0.1 mg/mL
PBS with no preservative; pH 7.2-7.4
Q08380
Lectin, galactoside-binding, soluble, 3 binding protein
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry, Western Blot
SP-2
Unconjugated
LGALS3BP
Liquid
LGALS3BP
IgG1
100 μg
4° C
Primary
3959
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