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A 804598, Tocris Bioscience™
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Catalog No. p-4816905
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective P2X7 antagonist

Potent, competitive P2X7 receptor antagonist (IC50 values are 8.9, 9.9 and 10.9 nM for mouse, rat and human P2X7 receptors respectively). Selective for P2X7 receptors (IC50 > 5-10 μM for a wide array of cell surface receptors and ion channels). Binds with high affinity (Ki app = 2.4 nM for rat P2X7 receptors).

Chemical Identifiers

CAS 1125758-85-1
Molecular Formula C19H17N5
Molecular Weight (g/mol) 315.38
InChI Key PQYCRDPLPKGSME-AWEZNQCLSA-N
Synonym d0q1po, 1-cyano-2-1s-1-phenylethyl-3-quinolin-5-yl guanidine, n-cyano-n'-1s-1-phenylethyl-n'-5-quinolinyl-guanidine, n-cyano-n-1s-1-phenylethyl-n'-5-quinolinylguanidine, e-n'-cyano-n-1s-1-phenylethyl-n-quinolin-5-yl guanidine, n-cyano-n'-1s-1-phenylethyl-n-quinolin-5-yl guanidine
PubChem CID 53325874
IUPAC Name 1-cyano-2-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine
SMILES CC(C1=CC=CC=C1)N=C(NC#N)NC2=CC=CC3=C2C=CC=N3

Specifications

Quantity 10 mg
Formula Weight 315.37
Percent Purity >99%
Chemical Name or Material A 804598

Safety and Handling

Recommended Storage Store at -20°C
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