AANAT Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-1921	Proteintech Group Inc 179901AP150UL	150 μL

Description

Arylalkylamine N-Acetyltransferase (AANAT) is the penultimate enzyme is melatonin synthesis. Hormonal melatonin has been implicated in sleep and circadian clock function. Large changes in the abundance of AANAT are believed to be responsible for the large day/night rhythms in melatonin synthesis in the pineal gland and retina. Most research shows that AANAT activity is regulated by controlling the steady-state levels of the protein. Recent research, however, suggests that another mechanism may also play a role in controlling melatonin production without altering AANAT protein and activity. This mechanism may explain the sudden physiological increase in circulating melatonin observed at the onset of the dark period in humans.

Specifications

• Antigen: AANAT
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: O88816, Q16613, Q64666
• Gene ID (Entrez): 11298, 15, 25120
• Immunogen: AANAT Fusion Protein Ag12422
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: AANAT

• Concentration: 0.28 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: AA NAT, AANAT, Serotonin acetylase, Serotonin N acetyltransferase, SNAT
• Gene Symbols: Aanat
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody