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Tocris Bioscience™ AAQ Chloride

Photoswitchable Kv channel blocker

Supplier:  Tocris Bioscience™ 5462/50

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Catalog No. 546250


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Description

Description

AAQ chloride is a photoswitchable Kv channel blocker (IC50 values are 2 and 64 μM at 500 nm and 380 nm respectively). Switches conformation from cis to trans at 500 nm and trans to cis at 380 nm. Exhibits minimal activity at Nav1.2 and L-type Ca2+ channels. Stimulates action potential firing of hippocampal neurons in vitro at 500 nm and restores visual responsiveness in blind mice at 380 nm.
Specifications

Specifications

N,N,N-Triethyl-2-oxo-2-[[4-[2-[4-[(1-oxo-2-propen-1-yl)amino]phenyl]diazenyl]phenylamino]ethanaminium chloride
Soluble to 20mM in DMSO
Observed MW: 443.97
50 mg
C23H30ClN5O2
>98%
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Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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