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AARS2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550195

Catalog No. PA550195


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Description

Description

The antibody detects endogenous levels of total AARS2 protein.

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain
Specifications

Specifications

AARS2
Polyclonal
Unconjugated
AARS2
Liquid
AARS2
Fusion protein corresponding to a region derived from internal residues of human Alanyl-tRNA synthetase 2, mitochondrial
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
1.3 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q5JTZ9, Q14CH7
AARSL, KIAA1270
Rabbit
IgG
100 μL
-20°C
Primary
224805, 57505
Documents
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