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ABCA7 Rat anti-Mouse, Clone: 7A1-144, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA524784

Catalog No. PIMA524784


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Description

Description

ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. The high expression levels of ABCA7 in peripheral leukocytes, thymus, spleen and bone marrow suggests a role in the immune system lipid homeostasis.
Specifications

Specifications

ABCA7
Monoclonal
1.3 mg/mL
tris glycine with 0.15M NaCl and 0.05% sodium azide; pH 7.5
Q91V24
ABCA-SSN, ABCXATP-binding cassette sub-family A member 7, ATP-binding cassette, sub-family A (ABC1), member 7, Autoantigen SS-N, EC 2.2.1.1, EC 3.6.3, EC 3.6.3.41, FLJ40025, Macrophage ABC transporter
Rat
IgG2a, kappa
100 μL
4° C, do not freeze
Primary
27403
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
7A1-144
Unconjugated
Abca7
Liquid
Abca7
Mouse ABCA7 stably-transfected HeLa cells.
Protein A
RUO
Antibody
Monoclonal
Mouse
Documents
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