ABCB1 Rabbit anti-Human, Mouse, Rat, Polyclonal , Abnova™
Rabbit polyclonal antibody raised against partial synthetic protein of human ABCB1.
Manufacturer: Abnova Corporation PAB29562
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq]Sequence: IYFKLVTMQTAGNEVELENAADESKSEIDA
|Immunohistochemistry (Frozen sections) (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to amino acids 621-650 at internal region of human ABCB1.|
|Immunogen affinity purification|
|Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed)|
|Rabbit polyclonal antibody raised against partial synthetic protein of human ABCB1.|
|Lyophilized from 0.9mg NaCl, 0.2mg Na|
|Store at −20°C. After reconstitution with 0.2mLof deionized water, store at 4°C for 1 month. For long term storage store at −20°C. Aliquot to avoid repeated freezing and thawing.|
|Human, Murine, Rat|
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