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ABCC5 Mouse anti-Human, Clone: OTI1F3, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF808329

Catalog No. 50-166-8780


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected; however, the complete sequence and translation initiation site is unclear.
Specifications

Specifications

ABCC5
Monoclonal
Unconjugated
ABCC5
Lyophilized
ABCC5
Full length human recombit protein of human ABCC5 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Western Blot
OTI1F3
PBS with 8% trehalose and no preservative; pH 7.3
O15440
ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11
Mouse
IgG2b
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
10057
SDS
Documents
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