ABCD1 Mouse anti-Human, Clone: OTI3A1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526606
DescriptionABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|ABCD1; ATP-binding cassette, sub-family D (ALD), member 1; ABC42; ALD; ALDP; AMN; adrenoleukodystrophy protein|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 508-745 of ABCD1 produced in E.coli|
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