Invitrogen™ ABCD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522246

Catalog No. PIPA522246

Description

Recommended positive controls: SHSY5Y. Predicted reactivity: Mouse (94%), Rat (92%), Chicken (85%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.

Specifications

• Antigen: ABCD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ABCD2
• Gene Alias: ABC39; Abcd2; adrenoleukodystrophy related; adrenoleukodystrophy-like 1; Adrenoleukodystrophy-related protein; ALD1; ALDL1; ALDR; ALDRP; ATP binding cassette subfamily D member 2; ATP-binding cassette sub-family D member 2; ATP-binding cassette, subfamily D (ALD), member 2; ATP-binding cassette, sub-family D (ALD), member 2; ATP-binding cassette, sub-family D, member 2; hALDR; LOW QUALITY PROTEIN: ATP-binding cassette sub-family D member 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 225
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.77 mg/mL
• Formulation: 0.1M Tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9UBJ2
• Gene Symbols: ABCD2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 338 and 588 of ABCD2 (Uniprot ID#Q9UBJ2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG