ABCD4 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA550903
ABCD4 Polyclonal Antibody detects endogenous levels of ABCD4 protein.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.
|Synthesized peptide derived from the Internal region of human ABCD4.|
|Antigen affinity chromatography|
|ELISA, Immunohistochemistry, Western Blot|
|PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4|
|ABCD4, PXMP1L, ATP-binding cassette sub-family D member 4, PMP70-related protein, P70R, Peroxisomal membrane protein 1-like, PXMP1-L, Peroxisomal membrane protein 69, PMP69|
|-20° C, Avoid Freeze/Thaw Cycles|
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