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ABCG5 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550538

Catalog No. PA550538


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Description

Description

The antibody detects endogenous levels of total ABCG5 protein.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.
Specifications

Specifications

ABCG5
Polyclonal
Unconjugated
ABCG5
Liquid
ABCG5
Synthetic peptide corresponding to residues near the N terminal of human ATP-binding cassette, sub-family G (WHITE), member 5
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
0.7 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q9H222
STSL
Rabbit
IgG
100 μL
-20°C
Primary
64240
Documents
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