ABCG5 Mouse anti-Human, Clone: 1B5E10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524799
DescriptionThe protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.
|PBS with 0.5% proprietary stabilizer and 0.05% sodium azide; pH 7.4|
|ATP-binding cassette sub-family G member 5, ATP-binding cassette, sub-family G (WHITE), member 5, ATP-binding cassette, subfamily G, member 5, sterolin 1, sterolin-1, STSL|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|Partial recombit human ABCG5 (between residues 300-500) expressed in E. coli.|
|Ammonium sulfate precipitation|
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