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Tocris™ ABT 724 trihydrochloride

Potent, selective D4 partial agonist; proerectile

Manufacturer:  Tocris™ 2214/50

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Catalog No. 22-145-0

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For Research Use Only



Potent dopamine D4 receptor partial agonist (EC50 = 12.4 nM; 61% efficacy vs. dopamine). Has no agonist activity at D2 receptors (EC50 > 10µM). Selective in rats in vivo; produces penile erection following i.c.v. administration; increases intracavernosal pressure and potentiates the proerectile effects of sildenafil following s.c. administration. Displays minimal side effects.
  • Chemical Name: 2-[[4-(2-Pyridinyl)-1-piperazinyl]methyl]-1H-benzimidazole trihydrochloride
  • Formula: C17H19N5.3HCl
  • CAS Number: 587870-77-7
  • Solubility: Soluble to 100mM in water
  • Purity: >99
Description & Specifications


ABT 724 trihydrochloride
ABT 724 trihydrochloride
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