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Tocris Bioscience™ AC 5216
Selective TSPO ligand
Supplier: Tocris Bioscience™ 5281/10
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Description
AC 5216 is a ligand of translocator protein (TSPO, peripheral benzodiazepine receptor). Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects.Specifications
>98% | |
AC 5216 | |
AC 5216 |
10 mg | |
401.46 |
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