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Thermo Scientific™ Acclaim™ HILIC-10 HPLC Columns

Use this HILIC column to retain and separate highly polar molecules that are unretained by reversed-phase chromatography.

Manufacturer:  Thermo Scientific™ 074257

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Catalog No. DX074257


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Description

Description

Separate highly hydrophilic molecules by hydrophilic interaction liquid chromatography using Thermo Scientific™ Acclaim™ HILIC-10 LC Columns. These columns retain and separate highly polar molecules that are unretained by reversed-phase chromatography. Their high-purity, spherical, porous silica base is covalently modified with a proprietary hydrophilic layer. This chemistry enables the use of 5–20% aqueous mobile phase while maintaining affinity for polar analytes. Sample throughput is increased without the need to evaporate and reconstitute samples dissolved in nonaqueous solvents.

Rugged and Reproducible Separations of Highly Polar Compounds:
  • Unique selectivity, complementary to reversed-phase columns
  • Enhanced sensitivity for MS detection
  • Hydrolytically stable
  • Rugged column packing
  • Broad application range, including separation of hydrophilic drugs and drug metabolites
Acclaim HILIC-10 LC columns are available in 3µm particle size and a variety of column formats: 4.6x150mm, for high-throughput routine analysis; 3.0x150mm, for high-throughput analysis with reduced solvent consumption; and 2.1x150mm, for LC-MS analysis.
Specifications

Specifications

HILIC
Spherical, Fully Porous, Ultrapure Silica
HILIC
Proprietary Polar Group
4.6 mm
LC/MS
8500 psi (590 bar)
2 to 8
300 m²/g
Proprietary
Analytical Column
8%
Yes
Analytical Column
0.8 to 1.5 mL/min
150 mm
3 µm
120 Å
70°C
Acclaim
SDS
Documents
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