Acetyl-Histone H2B (Lys12) Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA540100
DescriptionHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
|Acetyl-Histone H2B (Lys12)|
|KLH-conjugated synthetic peptide corresponding to human the region of histone H2B containing the acetylated lysine 12 (H2BK12ac).|
|Antigen affinity chromatography|
|ChIP assay, ChIP-sequencing, ELISA, Immunocytochemistry, Immunofluorescence, Peptide Array, Western Blot|
|PBS with 0.05% sodium azide; pH 7.4|
|H2BK12ac, Acetyl-Histone H2, HIST1H2BC, H2B, H2BFL, HIST1H2BC, H2BFH, H2BFA, Histone H2B.1 A, Histone H2B.a, H2B/a, Histone H2B.g, H2B/g, Histone H2B.h, H2B/h, Histone H2B.k, H2B/k, Histone H2B.I, H2B/I|
|-20°C or -80°C if preferred|
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