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Acetyl-Histone H4 (Lys12) Mouse anti-Human, Clone: 3HH4-4C10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA3058

Catalog No. MA3058


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Description

Description

MA3-058 detects Acetyl-Histone H4 Lys12 in Human samples. MA3-058 has been succesfully used in western blot and ELISA applications. Immunogen is a synthetic peptide corresponding to residues 1-24 of Human Acetyl-Histone H4 Lys12, which is highly conserved across multiple species.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Specifications

Specifications

Acetyl-Histone H4 (Lys12)
Monoclonal
Unconjugated
HIST1H4A
Liquid
HIST1H4A
Synthetic peptide corresponding to amino acids 1-24 of human Histone H4 coupled to ovalbumin: MSGRG(acetyl-K)GG(acetyl-K) GLG(acetyl-K)GGA(acetyl-K)RHRKVLR-C
50 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
8359
ELISA, Western Blot
3HH4-4C10
ascites with 0.05% sodium azide
P62805
H4FA, H4K12ac, H4K12a
Mouse
IgG1
RUO
Antibody
Monoclonal
Human
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