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Acetyl-Histone H4 (Lys8) Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA540092

Catalog No. PA540092


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Description

Description

Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called ""histone code"". Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases.
Specifications

Specifications

Acetyl-Histone H4 (Lys8)
Polyclonal
Unconjugated
HIST1H4A
Liquid
HIST1H4A
KLH-conjugated synthetic peptide corresponding to human the region of histone H4 containing the acetylated lysine 8 (H4K8ac).
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
ChIP assay, ELISA, Immunocytochemistry, Immunofluorescence, Peptide Array, Western Blot
1.23 mg/mL
PBS with 0.05% Proclin 300, 0.05% sodium azide; pH 7.4
P62805, P62806
H4K8ac, HIST1H4A, H4/A, H4FA, Histone H4, Histone H4A
Rabbit
IgG
50 μg
-20°C or -80°C if preferred
Primary
326619, 8359
Documents
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