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ACP6 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550441

Catalog No. PA550441


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Description

Description

The antibody detects endogenous levels of total ACP6 protein.

Lysophosphatidic acid phosphatase type 6 (ACP6), also designated acid phosphatase-like protein 1 (ACPL1) or lysophosphatidic acid phosphatase (LPAP), is a 428 amino acid secreted protein that hydrolyzes lysophosphatidic acid to monoacylglycerol. ACP6 is highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and exists as two isoforms as a result of alternative splicing events. The gene encoding ACP6 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease, familial adenomatous polyposis and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, maligt melanoma and multiple myeloma.
Specifications

Specifications

ACP6
Polyclonal
Unconjugated
ACP6
Liquid
ACP6
Fusion protein corresponding to residues near the C terminal of human acid phosphatase 6, lysophosphatidic
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1.2 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q9NPH0
ACPL1, LPAP
Rabbit
IgG
100 μL
-20°C
Primary
51205
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