ACPL2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA548756

Catalog No. PA548756

Description

Predicted to react with mouse and rat based on sequence homology.

Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1- 4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.

Specifications

• Antigen: ACPL2
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: Q8TE99
• Gene Symbols: PXYLP1
• Immunogen: KLH conjugated synthetic peptide between 306-335 amino acids from the Central region of human ACPL2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: PXYLP1
• Gene Alias: 2-phosphoxylose phosphatase 1, 313-, Acid phosphatase-like protein 2, Xylosyl phosphatase, epididymis luminal protein 124 {ECO:0000303/Ref2, ECO:0000312/EMBL:ACJ137311}, PXYLP1 (HGNC:26303)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 92370
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid