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Tocris™ ACT 462206

Potent, dual orexin receptor antagonist

Manufacturer:  Tocris™ 5319/10

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Catalog No. 53-191-0

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For Research Use Only



Potent, dual orexin receptor antagonist (IC50 values are 11 and 60nM for OX2 and OX1 receptors respectively). Exhibits anxiolytic-like properties in vivo. Brain penetrant.
  • Chemical Name: (2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide
  • Formula: C20H24N2O4S
  • CAS Number: 1361321-96-1
  • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
  • Purity: >99
Description & Specifications


ACT 462206
ACT 462206
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