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Drg International Inc Acth Elisa
Supplier: Drg International Inc EIA3647
An enzyme immunoassay for the quantitative determination of ACTH (Adrenocorticotropic Hormone) in plasma. ACTH (Adrenocorticotropic hormone) or corticotropin is a 39-amino acid peptide hormone (MW=4500) secreted by the pituitary to regulate the production of steroid hormones by the adrenal cortex. ACTH increases the synthesis and release of all adrenal sterioids, aldosterone, cortisol and adrenal androgens. It is the principal modulator of cortisol, the most important glucocorticoid in man. As the cortisol level in blood increases, release of ACTH is inhibited directly at the pituitary level. Through this same mechanism, decreasing cortisol levels lead to elevated ACTH levels. The DRG ACTH Immunoassay is a two-site ELISA (Enzyme-Linked Immunosorbent Assay) for the measurement of teh biologically active 39 amino acid chain of ACTH. A goat polyclonal antibody to human ACTH, and a mouse monoclonal antibody to human ACTH are specific for well defined regions on the ACTH molecule.
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