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ACTH Antibody (AH26), Alexa Fluor™ 750, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP233072AF750
Description
ACTH Monoclonal specifically detects ACTH in Human, Mouse, Rat samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.Specifications
ACTH | |
Monoclonal | |
Alexa Fluor 750 | |
50 mM sodium borate with 0.05% sodium azide | |
POMC | |
Synthetic peptide corresponding to aa1-24 of human ACTH (Uniprot: P01189) | |
0.1 mL | |
Primary | |
ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This monoclonal antibody is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).It also may react with other tumors (e.g. some small cell carcinoma | |
Store at 4°C in the dark. |
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
AH26 | |
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen | |
ACTH, adrenocorticotropic hormone, adrenocorticotropin, alpha-melanocyte-stimulating hormone, alpha-MSH, beta-endorphin, beta-LPH, beta-melanocyte-stimulating hormone, beta-MSH, CLIP, corticotropin-like intermediary peptide, corticotropin-lipotropin, gamma-LPH, gamma-MSH, lipotropin beta, lipotropin gamma, LPH, melanotropin alpha, melanotropin beta, melanotropin gamma, met-enkephalin, MSH, NPP, POC, pro-ACTH-endorphin, proopiomelanocortin, pro-opiomelanocortin, proopiomelanocortin preproprotein | |
Mouse | |
Protein A or G purified | |
Neuroscience, Nutrient Sensing in the Brain | |
5443.0 | |
Human, Mouse, Rat | |
IgG1 κ |
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