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Alfa Aesar™ Actinomycin D, 1mg/mL in DMSO, sterile-filtered

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Quantity:
1mL
5 x 1mL
50-76-0
C62H86N12O16
1255.438
MFCD00005033
RJURFGZVJUQBHK-HUZQGMAJSA-N
Dactinomycin; Actinomycin C1
131954673
2-amino-4,6-dimethyl-3-oxo-1-N-[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-9-N-[(3R,6S,7R,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,
CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C
50-76-0
C62H86N12O16
1255.438
MFCD00005033
RJURFGZVJUQBHK-HUZQGMAJSA-N
Dactinomycin; Actinomycin C1
131954673
2-amino-4,6-dimethyl-3-oxo-1-N-[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-9-N-[(3R,6S,7R,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,
CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C
Applications
Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm′s tumor and the sarcomas.

Solubility
Soluble in acetonitrilie or acetone at 10 mg/mL and in DMSO at a minimum of 1 mg/mL, slightly soluble in water.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Physical Form Liquid
Quantity 1mL
Chemical Name or Material Actinomycin D, 1mg/mL in DMSO, sterile-filtered

GHS H Statement
H227
Combustible liquid.

GHS P Statement
P210-P280-P370+P378a-P403+P235-P501a
Keep away from heat/sparks/open flames/hot surfaces.
- No smoking.
Wear protective gloves/protective clothing/eye protection/face protection.
In case of fire: Use for extinction: CO2, powder or water spray.
Store in a well-ventilated place.
Keep cool.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : AU1575000

storageNote1 : -30° to -10°C