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ACY1 Mouse anti-Human, Mouse, Clone: OTI1D4, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA503189

Catalog No. 50-167-4146


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Description

Description

ACY1 encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene. A related pseudogene has been identified on chromosome 18.
Specifications

Specifications

ACY1
Monoclonal
0.3 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q03154, Q99JW2
ACY-1, ACY1D, HEL-S-5
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
109652, 95
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
OTI1D4
Unconjugated
ACY1
Liquid
ACY1
Full length human recombit protein of human ACY1 produced in HEK293 cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human, Mouse
Documents
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