ADAM8 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA587946
Immunogen sequence: IAPSRPWALM EQYEVVLPWR LPGPRVRRAL PSHLGLHPER VSYVLGATGH NFTLHLRKNR DLLGSGYTET YTAANGSEVT EQPRGQDHCF YQGHVEGYPD SAASLSTCAG LRGFFQVGSD LHLIEPLDEG GEGGRHAVYQ AEHLLQTAGT CGVSDDSLGS LLGPRTAAVF RPRPGDSLPS RETRYVELYV VVDNAEFQML GSEAAVRHRV LEVVNHVDKL YQKLNFRVVL VGLEIWNSQD RFHVSPDPSV TLENLLTWQA RQRTRRHLHD NVQLITGVDF TGTT; Positive Samples: BxPC-3, NIH/3T3; Cellular Location: Membrane, Single-pass type I membrane proteinThis gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.
|Recombit fusion protein containing a sequence corresponding to amino acids 17-300 of human ADAM8|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|Antigen Affinity Chromatography|
|-20° C, Avoid Freeze/Thaw Cycles|
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