ADAM8 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA587946

Catalog No. PIPA587946

Description

Immunogen sequence: IAPSRPWALM EQYEVVLPWR LPGPRVRRAL PSHLGLHPER VSYVLGATGH NFTLHLRKNR DLLGSGYTET YTAANGSEVT EQPRGQDHCF YQGHVEGYPD SAASLSTCAG LRGFFQVGSD LHLIEPLDEG GEGGRHAVYQ AEHLLQTAGT CGVSDDSLGS LLGPRTAAVF RPRPGDSLPS RETRYVELYV VVDNAEFQML GSEAAVRHRV LEVVNHVDKL YQKLNFRVVL VGLEIWNSQD RFHVSPDPSV TLENLLTWQA RQRTRRHLHD NVQLITGVDF TGTT; Positive Samples: BxPC-3, NIH/3T3; Cellular Location: Membrane, Single-pass type I membrane protein

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: ADAM8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADAM8
• Gene Symbols: ADAM8
• Immunogen: Recombit fusion protein containing a sequence corresponding to amino acids 17-300 of human ADAM8
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Concentration: 5.68 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P78325, Q05910
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 101, 11501
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid