ADAMTS8 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA551350
The antibody detects endogenous levels of total ADAMTS8 protein. Peptide sequence: THKYAPFIII GLHLALGIFS FTLDTWSTSR GDTAEILGSG AGIACGSHVT Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% The antibody detects endogenous levels of total ADAMTS8 protein.This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms.
|Synthetic peptide of human ADAMTS8|
|Antigen affinity chromatography|
|PBS with 40% glycerol and 0.05% sodium azide; pH 7.4|
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