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ADAMTS8 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA551350

Catalog No. PA551350


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Description

Description

The antibody detects endogenous levels of total ADAMTS8 protein. Peptide sequence: THKYAPFIII GLHLALGIFS FTLDTWSTSR GDTAEILGSG AGIACGSHVT Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% The antibody detects endogenous levels of total ADAMTS8 protein.

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms.
Specifications

Specifications

ADAMTS8
Polyclonal
Unconjugated
ADAMTS8
Liquid
ADAMTS8
Synthetic peptide of human ADAMTS8
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1.6 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q9UP79
METH2
Rabbit
IgG
100 μL
-20°C
Primary
11095
Documents
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