p210bcr/abl kinase inhibitor
Manufacturer: Tocris 3716/50
Descriptionp210bcr/abl tyrosine kinase inhibitor (IC50 = 14µM). Induces apoptosis in T-lymphoblastic human leukemia cell lines (IC50 values range from 16.8 to 216.3nM) in vitro. Displays selectivity for chronic myelogenous leukemia (CML) myeloid progenitors in vitro.
- Chemical Name: 4-[[(2,5-Dihydroxyphenyl)methyl]amino]benzoic acid tricyclo[22.214.171.124,7]dec-1-yl ester
- Formula: C24H27NO4
- CAS Number: 241127-58-2
- Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
- Purity: >98
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