Tocris™ Adaphostin

p210bcr/abl kinase inhibitor

Manufacturer: Tocris™ 3716/10

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Catalog No. 37-161-0R

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For Research Use Only


    Product Type Adaphostin
    Inhibitors Adaphostin
    Purity >98
    Molecular Weight 393.48
    Quantity 10mg

    p210bcr/abl tyrosine kinase inhibitor (IC50 = 14µM). Induces apoptosis in T-lymphoblastic human leukemia cell lines (IC50 values range from 16.8 to 216.3nM) in vitro. Displays selectivity for chronic myelogenous leukemia (CML) myeloid progenitors in vitro.

    • Chemical Name: 4-[[(2,5-Dihydroxyphenyl)methyl]amino]benzoic acid tricyclo[,7]dec-1-yl ester
    • Formula: C24H27NO4
    • CAS Number: 241127-58-2
    • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
    • Purity: >98

  • Description & Specifications

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