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Tocris Bioscience™ Adaptaquin

HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant

Supplier:  Tocris Bioscience™ 5953/10

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Catalog No. 59-531-0


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Description

Description

Adaptaquin is a HIF-prolyl hydroxylase-2 (PHD2) inhibitor. Blocks glutamate induced ROS production in HT-22 cells, independent of MnSOD. Exhibits neuroprotective effects and enhances functional recovery in rodent intracerebral hemorrhage models, via inhibition of ATF4 dependent genes. Brain penetrant. Also antioxidant.
Specifications

Specifications

7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol
10 mg
C21H16ClN3O2
>97%
385786-48-1
Hydrolase Inhibitors
377.82
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Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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