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Adenylosuccinate lyase Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 152641AP

Catalog No. 50-173-0102


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Description

Description

ADSL (adenylosuccinate lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid protein that is involved in both purine biosynthesis and in the formation of adenosine monophosphate (AMP) from inosine monophosphate. Expressed ubiquitously, ADSL catalyzes two key reactions in AMP biosynthesis, namely the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and the subsequent removal of fumarate from adenylosuccinate to yield AMP. Defects in the gene encoding ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency), an autosomal recessive disorder characterized by epilepsy, growth retardation and muscular wasting. Multiple isoforms of ADSL exist due to alternative splicing events.
Specifications

Specifications

Adenylosuccinate lyase
0.22 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P30566, P54822
Adenylosuccinase, adenylosuccinate lyase, ADSL, AMPS, ASASE, ASL
Rabbit
IgG
150 μL
-20°C
Primary
11564, 158, 315150
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
ADSL
Liquid
ADSL
Adenylosuccinate lyase Fusion Protein Ag7332
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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