ADFP Mouse anti-Human, Clone: 2C5A3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524797
DescriptionMilk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase. ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to specific cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. ADFP may be a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.
|PBS with 0.5% proprietary stabilizer and 0.05% sodium azide; pH 7.4|
|ADFP, Adipophilin, Adipose differentiation-related proteinadipophilin, ADRP, MGC10598, perilipin 2, perilipin-2|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Partial recombit human ADFP (between residues 200-437) expressed in E. coli.|
|Ammonium sulfate precipitation|
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