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Adiponectin/Acrp30 Mouse anti-Human, Alexa Fluor™ 594, Clone: ADPN/1370, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP254319AF594

Catalog No. NP24319A94


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Description

Description

Adiponectin/Acrp30 Monoclonal antibody specifically detects Adiponectin/Acrp30 in Human samples. It is validated for Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin).
Specifications

Specifications

Adiponectin/Acrp30
ADPN/1370
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Conjugated, Purified
ADIPOQ
Recombinant human Adiponectin protein fragment
Protein A or G purified
Diabetes Research, Lipid and Metabolism
Primary
9370.0
Human
ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin)
Alexa Fluor™ 594
50 mM sodium borate with 0.05% sodium azide
ACDC, ACRP30ADPN, adipocyte, C1Q and collagen domain containing, adiponectin, adiponectin, C1Q and collagen domain containing, AdipoQ, ADIPQTL1, apM-1, APM1APM-1, C1q and collagen domain-containing protein, GBP28apM1, Gelatin-binding protein
Mouse
IgG2b
0.1 mL
Store at 4°C in the dark.
Monoclonal
This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism.
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