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AEG 3482, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Inhibitor of c-jun N-terminal kinase (JNK) signaling. Binds Hsp90 and facilitates HSF1 release, induces expression of Hsp70, which in turn blocks JNK activation and JNK-dependent apoptosis. Antiapoptotic; inhibits NGF withdrawal-induced death in SCG neurons (EC50 = 20 μM).
Specifications
Quantity | 50 mg |
Formula Weight | 280.33 |
Percent Purity | >99% |
Chemical Name or Material | AEG 3482 |
Safety and Handling
Recommended Storage : Store at Room Temperature